Electrode-enabled microplates (iPlate™) for high-throughput screening (HTS) applications, compatible with existing robotic and readout detection systems.
About the Technology
iFluidics technology consists of novel programmable, microfluidics-based systems on a chip and associated assay design software that enable rapid, accurate quantification of proteins, enzyme activity, and nucleic acids. The technologies allow investigators to concentrate solutes, separate and move molecules based on electrokinetic properties, and optimize mixing at very low reaction volumes (< 5 muL). Based on platforms developed at UCSB by Igor Mezic and Frederic Bottausci, the mufCPU platforms are widely applicable to biological research assays, particularly to high-throughput screening, for which reagent costs can be dramatically reduced. In the near term, these platforms are expected to change the landscape for clinical point-of-care diagnostics, by enabling routine screening for conditions that are currently excluded for cost, time, sensitivity, or accuracy reasons.
About the iPlate
Microtiter plates are in wide use in biological assays. iFluidics has developed an active microtiter plate platform - the iPlate, in which the shape form is that of a standard microtiter plate, but the bottom is equipped with electrodes that open the possibility of the full array of mufCPU manipulations inside a well. While the effectiveness of the iPlate platform is already proven in high well number settings (1536, 3456), the first line of iPlate products is in 96-well format, targeting the research and diagnostics ELISA market.